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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP2A2
All Species:
37.88
Human Site:
S566
Identified Species:
75.76
UniProt:
O94973
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94973
NP_036437.1
939
103960
S566
Q
D
V
L
R
S
D
S
Q
L
R
N
A
D
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116794
953
104990
S542
Q
D
V
L
R
S
D
S
Q
L
R
N
A
D
V
Dog
Lupus familis
XP_533200
1007
111388
S638
Q
D
V
L
R
S
D
S
Q
L
K
N
A
D
V
Cat
Felis silvestris
Mouse
Mus musculus
P17427
938
104082
S566
Q
D
V
L
R
S
D
S
Q
L
K
N
A
D
V
Rat
Rattus norvegicus
P18484
938
104026
S566
Q
D
V
L
R
S
D
S
Q
L
K
N
A
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012914
938
104174
S566
Q
D
V
L
R
S
D
S
Q
L
K
N
A
D
V
Frog
Xenopus laevis
NP_001089303
939
104392
S567
Q
D
V
L
R
S
D
S
Q
L
R
N
A
D
V
Zebra Danio
Brachydanio rerio
XP_001922436
930
103267
S567
Q
E
V
L
R
S
D
S
Q
I
R
N
S
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91926
940
105602
S567
Q
D
V
F
R
Q
H
S
N
L
R
S
A
D
A
Honey Bee
Apis mellifera
XP_394621
937
104937
S567
Q
D
V
F
R
Q
H
S
N
L
R
S
A
D
A
Nematode Worm
Caenorhab. elegans
NP_509572
925
104161
H566
Q
Q
V
F
Q
T
D
H
N
L
R
N
P
D
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38065
1025
114993
L627
I
K
F
F
Q
L
E
L
N
S
L
D
I
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.6
89.3
N.A.
97.2
97.2
N.A.
N.A.
95.3
87.6
84.3
N.A.
69.8
71
66.1
N.A.
Protein Similarity:
100
N.A.
94.5
91.3
N.A.
98.6
98.8
N.A.
N.A.
97.7
94.2
91.1
N.A.
81.4
82.2
78.4
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
100
80
N.A.
60
60
46.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
66.6
66.6
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
75
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
75
0
0
0
0
75
0
0
0
0
9
0
92
0
% D
% Glu:
0
9
0
0
0
0
9
0
0
0
0
0
0
9
0
% E
% Phe:
0
0
9
34
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
17
9
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
34
0
0
0
0
% K
% Leu:
0
0
0
67
0
9
0
9
0
84
9
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
34
0
0
75
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
92
9
0
0
17
17
0
0
67
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
84
0
0
0
0
0
59
0
0
0
0
% R
% Ser:
0
0
0
0
0
67
0
84
0
9
0
17
9
0
0
% S
% Thr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
92
0
0
0
0
0
0
0
0
0
0
0
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _